Clinical Impact of Everolimus Cumulative Dose on Pancreatic Neuroendocrine Tumors (pNETs) Outcome Abstract #840
Introduction: Everolimus is approved for advanced pancreatic neuroendocrine tumors (pNETs).
Aim(s): To evaluate the effect of cumulative dose (CD) on survival in patients (pts) treated with everolimus for advanced pNETs.
Materials and methods: Twelve pts with advanced pNETs were treated with everolimus. Pts were stratified into two groups with CD<1500 mg (Group A) v. CD≥1500 mg (Group B). ROC curve analysis was performed to determine the 1500 mg cut-off value. Overall survival (OS) was estimated using Kaplan-Meier method.
Conference: 11th Annual ENETS Conference (2014)
Category: Medical treatment - Targeted therapies
Presenting Author: Rossana Berardi
Authors: Berardi R, Torniai M, Onofri A, Partelli S, Guglielmi S, Gucciardino C, Savini A, Ferretti B, Enrica T, Giustini L, Falconi M, Cascinu S
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