Dedifferentiation of Metastatic Pancreatic Neuroendocrine Neoplasms

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Introduction: Neuroendocrine neoplasms (NENs) exhibit significant differences in growth behavior. Their metastatic disease may dedifferentiate presenting a more aggressive biological behavior

Aim(s): Prevalence of dedifferentiation of metastatic pancreatic NENs (pNENs)

Materials and methods: Dedifferentiation was defined by new biopsy of metastasis and the identification of a higher Ki-67 to increase the grade of differentiation

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Alexandraki K, Boutzios G, Kaltsatou M, Nikolopoulos G, Moschouris P,

Keywords: dedifferentiation,