Diagnostic and Outcome Differences between Sporadic and Familial Cases of Medullary Thyroid Cancer: A Retrospective Cohort Study Abstract #864

Introduction: Hereditary Medullary Thyroid Cancer (MTC) accounts for 20-30% of cases and has some clinically relevant peculiarities.
Aim(s): To analyze differences in diagnosis and outcome between sporadic and familial cases of MTC.
Materials and methods: All genotyped patients with MTC (n=35) diagnosed at Hospital Clinico San Carlos between 1984-2012 were included; 40% were germline mutation carriers (38.5% ATA-A, 53.9% ATA-B/C, 7.6% ATA-D). Median follow-up was 55 months (IQR 16-94). A comparative analysis was performed using Mann-Whitney U test, chi-squared test and Breslow test.
Conference: 11th Annual ENETS Conference 2014 (2014)
Category: Epidemiology/Natural history/Prognosis - Prognosis
Presenting Author: Guillermo Ropero Luis

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