Differential Expression of Markers in a Midgut Carcinoid Tissue Microarray Abstract #508

Introduction: Molecular mechanisms driving well-differentiated midgut carcinoid (MGC) tumors are not well-established. To pursue higher resolution tumor diagnostics, we studied a panel of markers for their expression in MGC, including: serotonin, FGF2, b-catenin, and E-cadherin, in primary, lymph node, and liver metastases.
Aim(s): To determine the differential expression of multiple tumor markers in an array of MGC specimens.
Materials and methods: A tissue microarray of primary SI-NETs (n=28) and lymph node metastases (LN-mets, n=24) was assessed by immunohistochemistry for expression of serotonin, FGF2, ß-catenin, E-cadherin and cadherin 17.
Conference: 9th Annual ENETS Conference (2012)
Category: Basic
Presenting Author: Eric Liu

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