Gastric GIST with synchronous neuroendocrine tumor of the pancreas, Case Report and Literature Review

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Introduction: The Gastrointestinal Stromal Tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. These are rare tumors with an incidence of 15 new cases per million per year. They often occur in individuals over the age of 40 years, without gender predominance. The clinical behavior is variable and benign tumors are the most common. They can develop anywhere in the GI tract, but are more frequent in the stomach and small intestine. The primary treatment, when located, is the surgical resection, which can be complemented with the use of imatinib. The occurrence of neuroendocrine tumors of the pancreas is rare, representing 1-5% of pancreatic cancers, and it is estimated that its incidence does not exceed 5 to one million. The tumors considered nonfunctioning (15-32% of pancreatic neuroendocrine tumors) are not associated with any syndrome, and are usually incidental. They have a slight predominance in males, and are more frequent in the 6th decade of life. Nonfunctioning tumors of islet cells are virtually all malignant tumors, and the treatment consists of surgical resection.

Aim(s): Evaluate the prevalence of both tumors synchronously, and characterize the affected population

Materials and methods: case report and literature review

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Tavares A

Authors: Tavares A, Ferreira A, Arruda Viveiros F, Cidade C, Maciel J,

Keywords: gastric GIST, pancreatic neuroendocrine tumor, synchronous,