Is the Classification of Functioning-PanNET/Non-Functioning PanNET Properly? Insulinoma/Non-Insulinoma Is More Suitable to Distinguish the Clinicopathological and Prognosis Difference of Localized Insulinoma

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Introduction: Pancreatic neuroendocrine tumor (PanNET) is classified into Functioning (F-PanNET) and Non-functioning (NF-PanNET) by hormone secretion. But insulinoma is slowly proliferating with unique features compared with Non-insulinoma F-PanNET (NiF-PanNET).

Aim(s): To compare the clinical features and prognosis of insulinoma with NF-PanNET and NiF-PanNET.

Materials and methods: Cohort 1 is retrospective data of 505 R0 resected PanNET at one institute from January 2004 to May 2015. Cohort 2 is 1370 regional/localized and 1197 distant PanNET from SEER database.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: yu x

Authors: Gao H, Yu X,

Keywords: pancreatic neuroendocrine tumor, insulinoma, functionality, prognosis, Ki-67,

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