Multimodal Endoscopic Diagnostics of Gastric Type I Neuroendocrine Tumors

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Introduction: From 1998 till 2014 in our institution we have diagnosed 72 type I gastric neuroendocrine tumors (NET) with upper gastrointestinal endoscopy.

Aim(s): At early stage (up to 2006) only white-light endoscopy was used for gastric NET diagnostics and all of them appeared as flat or polypoid reddish lesions in proximal stomach or gastric corpus. Since 2007 we started use narrow-band imaging (NBI) endoscopy and it allowed more accurate gastric NET diagnostics.

Materials and methods: All lesions with NBI examination had altered mucosal pit pattern: tortuous or dot-type. Moreover, with NBI it is possible to review not only pit pattern, but microvessel pattern also, and in all type I gastric NET we observed pathologic arborescent dilated microvessels. Use of NBI endoscopy with x150 magnification allowed comprehensive diagnostics of very small (less than 0,1 cm) lesions, and additional 43,2% gastric type I NETs were found only with such diagnostic approach.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Sokolov V, Pirogov S, Karpova E, Pavlov P, Sokolov D,

Keywords: confocal laser endomicroscopy, mucosal surface destruction, gastric NET ,