Neurokinin A Levels Predict Survival in Patients with Well-Differentiated Small Bowel Neuroendocrine Tumors Abstract #594

Introduction: Recent European investigations demonstrated that persistently elevated (> 50 pg/ml) plasma neurokinin A (NKA) levels are associated with poor short-term survival in patients with midgut neuroendocrine tumors (NETS).
Aim(s): We hypothesized that US patients with persistently elevated NKA levels (> 50 pg/ml) will also have poor short-term survival.
Materials and methods: Serial plasma NKA levels were collected from the charts of 183 patients with metastatic midgut NETS. Patients were grouped according to their NKA values, and survival rates were calculated. Group one had NKA levels < 50pg/ml. Group two patients at one point had NKA levels >50 pg/ml but are currently < 50pg/ml. Group three had NKA values currently and consistently >50pg/ml.
Conference: 10th Annual ENETS Conference (2013)
Category: Biomarkers
Presenting Author: Eugene Woltering

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