Pancreatic Neuroendocrine Tumor and Ileal Carcinoid in Acromegaly. Pluriglandular Association in Non-MEN 1 Patient: A Case Report. Abstract #1053

Introduction: Pluriglandolar endocrine disease in patients without familial inherited disease (non-MEN 1) are very rare. Primary Pancreatic Neuroendocrine Tumors (pNET) and ileal carcinoid tumors have different embryologic origin (foregut and midgut respectively).
Aim(s): To report the clinical and pathological features of a patient with syncronous GH secreting pituitary adenoma, primary pNET and ileal (midgut) carcinoid.
Materials and methods: A 66 years old man with acromegaly due to a GH-secreting pituitary adenoma, was referred to our center because of the incidental finding at CT-scan of a 8,7 cm round cystic lesion at the pancreatic tail. It was detected also a 3 cm solid hypervascular lesion in the mesenteric context and a hypervascular lesion in the small gut suggesting a midgut carcinoid with lymph-node metastasis. 68Ga-DOTA-NOC PET/CT showed focal uptake in all abdominal lesions confirming their NE nature. High serum 5HT levels were found while urinary 5-HIAA was normal.
Conference: 12th Annual ENETS Conference 2015 (2015)
Category: Clinical cases/reports
Presenting Author: Doctor Valbona Lico

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