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Introduction: Everolimus increases PFS in patients with advanced NETs. Currently, no biomarkers are available for early selection of patients who will benefit from everolimus. Everolimus can reduce VEGF-A production by tumor cells.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author:
Authors: Brouwers A, Van Asselt S, Oosting S, De Jong J, Lub-de Hooge M,
Keywords: neuroendocrine tumors, 89Zr-bevacizumab PET, VEGF-A, everolimus, biomarker,
#676 Gene Silencing by Promoter Hypermethylation in SI-NETs
Introduction: Aberrant DNA methylation is an important feature of human cancer affecting corresponding gene expressions and clinical features in different tumors, including SI-NETs.
Conference: 10th Annual ENETSConcerence (2013)
Presenting Author:
Authors: Fotouhi O, Hashemi J, Kjellman M, Höög A, Zedenius J,
Keywords: SI-NET,
#471 Alterations of Global and Gene-Specific DNA Methylation in Midgut Carcinoids
Introduction: Epigenetic alterations of DNA methylation are known to be associated with the clinical presentation of midgut carcinoids.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Fotouhi O, Hashemi J, Kjellman M, Höög A, Zedenius J,
Keywords: midgut carcinoid, methylation,
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