Analysis of Somatostatin Receptors Expression in Neuroendocrine Tumors

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Introduction: Clinical studies have suggested anti-tumor efficacy of somatostatin analog (SSA) in the treatment of neuroendocrine tumors (NETs).

Aim(s): We investigated the prognostic significance of expression of somatostatin receptors (SSTRs) in patients with NETs generally, and in a subset of patients treated with SSA.

Materials and methods: We evaluated immunohistochemical expression of SSTR1, 2, 3 and 5 in a cohort of archival NETs. We correlated expression levels with clinical outcomes after adjusting for other clinical prognostic variables.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Li T

Authors: Li T, Qian Z, Ter-Minassian M, Chan J, Brais L,

Keywords: SSTR2, SSA, NET, OS, PFS,