Focal Nesidioblastosis in an Adult Abstract #339
Introduction: Nesidioblastosis is an uncommon cause of persistent hyperinsulinemic hypoglycemia (PHH) in adults. Although it is well-described in infants, the pathophysiology in adults is poorly understood.
Aim(s): From our review of the literature, we believe that this is the second reported case of localized nesidioblastosis in an adult.
Materials and methods: A 63-year-old woman presented with unexplained weakness and dizziness, which was relieved with food intake. On workup, she was found to be hypoglycemic, with serum glucose values between 32 and 50 mg/dL. Magnetic resonance imaging revealed a nodule arising from the corpus of the pancreas, which was slightly enhanced, measuring 1.0 cm in diameter.
Conference: 8th Annual ENETS Conference (2011)
Presenting Author: Prof.Dr. Zafer N Canturk
To read results and conclusion, please login ...
Further abstracts you may be interested in
#1057 Localisation of Insulinoma and Beta-Cells: Comparison of Glucagon-Like Peptide-1 Receptor (GLP1-R) SPECT/CT, PET/CT and MRI. Preliminary Results of a Prospective Clinical Study.
Introduction: SPECT/CT imaging with GLP1-R specific radiotracers like 111In-DOTA-exendin-4 have already proved to be a useful tool for the preoperative localisation of insulinomas. PET/CT has several advantages over SPECT/CT: lower radiation exposure, less time consumption and higher spatial resolution.
Conference: 12th Annual ENETS Conference (2015)
Category: Imaging (radiology, nuclear medicine, endoscopy)
Presenting Author: Dr. Christof Rottenburger
Introduction: Pathologic hyperplasia of pancreatic endocrine cells is uncommon. ß cell hyperplasia contributes to persistent hyperinsulinemic hypoglycemia. The manifestations of patients with pancreatic ß cells hyperplasia are variable and their preop. diagnosis is difficult.
Conference: 9th Annual ENETS Conference (2012)
Presenting Author: Dr. Tsann Long Hwang
Keywords: ß cell hyperplasia
#1295 Intra-Operative Portal Vein Insulin Assay Combined with Occlusion of the Pancreas for Complicated Pancreatogenous Hypoglycemia
Introduction: Pancreatogenous hypoglycemia is a rare endocrine disorder. The precise localization of hypersecreting tissue and determination of complete resection are two main challenges for complicated pancreatogenous hypoglycemia, such as multiple endocrine neoplasia syndromes type-1 (MEN-1) and nesidioblastosis.
Conference: 13th Annual ENETS conference (2016)
Category: Surgical treatment
Presenting Author: Yang Zhiying
#699 Ethanol Ablation in an 81-Year-Old Patient with Pancreatic Neuroendocrine Tumor (Islet Cell Tumor) and Severe Hypoglycemia – A Case Study.
Introduction: The key clinical problem in patients with islet cell tumors are persistent hypoglycemia episodes, which are particularly dangerous in the elderly since neuroglycopenia may be the cause of stroke.
Conference: 10th Annual ENETS Conference (2013)
Category: Clinical cases/reports
Presenting Author: Elżbieta Andrysiak-Mamos
#2249 Pasireotide as a Possible Tool for the Control of Refractory Hyperinsulinemic Hypoglycemia from Malignant Insulinoma
Introduction: The control of hypoglycemic hyperinsulinemic syndrome from malignant insulinoma is challenging because it is often refractory to diazoxide and somatostatin analogues (SA). Everolimus can have side effects that can limit its use. Pasireotide, a multi-receptor-targeted SA with a high binding affinity to SSTR1 and SSTR5, exhibits a strong inhibitory effect of insulin secretion.
Conference: 15th Annual ENETS conference (2018)
Category: Case reports
Presenting Author: MD Maria Vittoria Davì