Intra and Interobserver Reproducibility of CT and MRI for Measurement of Liver Metastasis as a Basis of RECIST Evaluation in Patients with Neuroendocrine Tumors

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Introduction: The reliability of RECIST evaluation in patients with NET has not yet been analyzed.

Aim(s): To determine intra and interobserver reproducibility of CT and MRI for the measurement of NET liver metastases.

Materials and methods: Retrospective study on 54 patients with well-differentiated NET liver metastasis (22 patients underwent CT and 32 MRI). Patients were treatment-naïve or under somatostatine analogs. We analyzed triphasic abdominal CT or liver MRI (T2, T1 and T1 after injection of gadolinium on HAP and PVP). A maximum of five liver target lesions per patient was defined and three radiologists independently measured those target lesions on each sequence, in two sessions. A total of 1,656 measurements for CT and 3,384 for MRI were analyzed.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Arfi Rouche J, Foulon S, Caramella C, Ternes N, Planchard D,

Keywords: CT, MRI, liver, metastasis, reproducibility, RECIST,

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