Nonfunctional Pancreatic Neuroendocrine Tumor (NF PNET) Imaging and Evaluation Using 18F-FDG and 68Ga- DOTANOC-PET/CT: Initial Data of a Prospective Study

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Introduction: Predicting aggressive behavior of NF PNET still remains controversial. It is known that lymph node metastases are rare but possible also on small (1-2 cm) NF-PNET. Positive 18F-FDG-PET/CT avidity is associated with poor prognosis in NETs.

Aim(s): To evaluate the possibility to enhance diagnostic accuracy by using dual trace functional imaging 18F-FDG and 68Ga-DOTANOC PET/CT in patients with NF PNET.

Materials and methods: In this prospective study 29 patients underwent PET-imaging with two tracers, 18F-FDG and 68Ga-DOTANOC, followed by surgery or endoscopic ultrasonography biopsies (EUS-FNA) with follow-up. The imaging results were compared to a histology report.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Kauhanen O

Authors: Majala S, Seppänen H, Kemppainen J, Arola J, Schalin-Jäntti C,

Keywords: pancreatic neuroendocrine tumors, nonfunctional, incidentaloma, positron emission tomography, diagnosis,