Introduction: Hepatic metastases of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) may induce prognosis relevant complications in an otherwise stable systemic disease after resection of the primary.
Aim(s): To determine the period by which the CT guided high-dose-rate brachytherapy (HDR-BT) of rapidly growing liver metastases can delay the onset of palliative systemic therapy with otherwise stable disease course.
Materials and methods: Retrospective, monocentric observational study of 23 patients with a total of 37 CT-guided HDR brachytherapy (HDR-BT) sessions were evaluated for the delay of a systemic therapy escalation by individual, highly selective HD-BRT in oligotopic hepatic progression. Additional endpoints were local tumor control (LTC), progression-free survival (PFS) and overall survival (OS). HDR-BT was initiated by a ENETS multidisciplinary team (MDT) meeting vote.
Conference: 17th Annual ENETS Conference 2020 (2020)
Category: Imaging and Interventions (radiology, endoscopy)
Presenting Author: Dr. med. Henning Jann
, Jann H
, Jonczyk M
, Boening G
, Wieners G
, Geisel D
, Pavel M
, Gebauer B
, Wiedenmann B
, Fehrenbach U
, Denecke T
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