Pancreatic Polypeptide Cell Hyperplasia Associated with Nonfunctioning Pancreatic Neuroendocrine Tumor: A Case Report

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Introduction: A case report of pancreatic polypeptide (PP) cell hyperplasia in association with nonfunctioning pancreatic neuroendocrine tumor (NET).

Aim(s): A case of PP cell hyperplasia associated with a nonfunctioning pancreatic NET in a 55-year-old man with diabetes type 2 is reported.

Materials and methods: Urographic imaging, performed because of renal stones, incidentally showed a pancreatic head lesion that was subsequently resected by pancreaticoduodenectomy. Histological examination showed a NET (5.1 cm in diameter, grade 2) in processus uncinatus, associated with nesidiodysplasia and PP cell hyperplasia.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Prazic A, Ljungberg O, Nordenström E,

Keywords: pancreas, neuroendocrine tumor, islets of Langerhans, pancreatic polypeptide, hyperplasia, pancreatectomy,

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