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#564 Genetic Alterations in Glucagon Cell Adenomatosis

Introduction: Glucagon cell adenomatosis (GCA) was recently recognized by us as a multifocal neoplastic disease of the endocrine pancreas unrelated to MEN-1. Multiple micro- and a few macrotumors are found on the background of a hyperplasia of glucagon cells. The disease may cause unspecific abdominal symptoms and only rarely a glucagonoma syndrome. Recently a mutation in the glucagon receptor (GCGR) gene was described in one GCA patient.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Henopp T, Anlauf M, Biskup S, Klöppel G, Sipos B,

Keywords: glucagon,