FOXM1 Is Strongly Associated with Cell Proliferation and Is Not Influenced by Metabolic Syndrome in GEP-NETS Abstract #1810

Introduction: Gastro-entero-pancreatic neuroendocrine tumors(GEP-NETs) and metabolic syndrome(MS) are both increasing exponentially. MS has been associated with several non NET cancers.
Aim(s): To evaluate the influence of MS and their individual criteria in GEP-NETs expression of cell proliferation and inflammation molecular markers.
Materials and methods: IHC studies for Ki-67, FOXM1, IGF1R and IL-6 were performed in GEP-NETs paraffin-embedded tissue(n=39) and its expression was quantified by computerized image analysis.
Conference: 14th Annual ENETS conference (2017)
Category: Basic Science - Signaling pathways, receptors, biomarkers
Presenting Author: Dr. Ana Paula Santos

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