Abstract Library
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ENETS Abstract Search
Introduction: DNA-targeting agents are the main treatment of aggressive pulmonary and pancreatic neuroendocrine carcinomas (NEC). FOXM1 is a transcription factor controlling cell proliferation and DNA repair pathways, playing therefore an important role in tumor progression and chemoresistance.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Cros J
Authors: De Rycke O, Raffenne J, Lacombe C, Hentic O, Gounant V,
Keywords: neuroendocrine carcinoma, FOXM1, DNA repair, anti-tumor drug,
Introduction: G3 gastroenteropancreatic neuroendocrine tumors (G3 NET) and carcinomas (G3 NEC) differ considerably concerning their biological behavior and patients outcome. Whereas the WHO2017 classification for pancreatic NETs proposes a distinction of both groups using the Ki-67 proliferation marker (Klöppel et al. Reviews and Reports 2017), a useful marker for the subclassification of G3 intestinal NETs have not been recommended until now.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Briest F
Authors: Briest F, Konukiewitz B, Anlauf M, Klöppel G, Grabowski P,
Keywords: gastroenteropancreatic neuroendocrine tumors, GEP-NET, NET G3, NEC G3, Tumor marker, FOXM1, Ki-67, differentiation,
Introduction: Gastro-entero-pancreatic neuroendocrine tumors(GEP-NETs) and metabolic syndrome(MS) are both increasing exponentially. MS has been associated with several non NET cancers.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Pereira R
Authors: Pereira R, Pereira S, Morais T, Costa M, Sampaio P,
Keywords: GEP-NETs, metabolic syndrome, FOXM1, IGF1R, IL-6, Ki67 ,
Introduction: Bronchial neuroendocrine neoplasias comprise a wide spectrum of well-differentiated tumors (typical/atypical carcinoids) to undifferentiated carcinomas such as small (SCLC) and large cell (LC) neuroendocrine carcinomas with a fatal prognosis. Therapeutic options are unsatisfactory.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author: Lewens F
Authors: Lewens F, Freitag H, Briest F, Heilmann M, Schneider C,
Keywords: bronchial, NETs, PI3K, FoxM1, survivin, cell lines, SCLC,
Introduction: Forkheadbox proteins (Fox proteins) are transcriptions factors. They are highly conserved key players in a large number of cellular processes. Fox proteins have been described as acting as both tumor suppressors and oncogenes. Most notably, they operate in the context of the majority of cancer-related pathways. Information about the fuunction of these proteins in gastroenteropancreatic neuroendocrine neoplasias is scant.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author: Briest F
Authors: Briest F, Freitag H, Lewens F, Kaemmerer D, Hörsch D,
Keywords: Forkheadbox proteins, signalling network, immunohistochemistry, siRNA, microarray technique,