Consensus papers & position statements
Expert consensus on specific clinical and scientific questions, developed by the ENETS Advisory Board, addressing key areas of neuroendocrine neoplasia (NEN), particularly where high-quality evidence is limited or evolving.
2025 expert consensus papers – Controversies in NEN
The ENETS Controversies in Neuroendocrine Neoplasms series, published in the Journal of Neuroendocrinology (JNE), provides expert consensus on selected clinical and scientific questions in areas where evidence is limited, evolving or subject to ongoing debate.
Developed by multidisciplinary experts within the ENETS community, each paper is based on a structured review of the available evidence and offers practice-oriented considerations to support clinical decision-making.
Five papers are currently available in JNE with free access:
- Controversies in NEN: An ENETS position statement on nutritional support in neuroendocrine neoplasms
Simona Grozinsky-Glasberg, Johannes Hofland, Stephanie Alband, Yasmin Chotai de Lima, Adina Croitoru, Wanda Geilvoet, Peter Igaz, Beata Kos-Kudła, Guenter J. Krejs, Alessandro Laviano, Francesco Panzuto, Anguraj Sadanandam, Ana Paula Santos, Staffan Welin, Rajaventhan Srirajaskanthan
Journal of Neuroendocrinology | Volume 37, Issue 12 | First published: 25 June 2025 - Controversies in NEN: An ENETS position statement on the endoscopic management of localised gastric, duodenal and rectal neuroendocrine neoplasms
Francesco Panzuto, Dermot O'Toole, Günter Klöppel, Ulrich Peter Knigge, Günter Josef Krejs, Marina Tsoli, Marco Volante, Tu Vinh Luong
Journal of Neuroendocrinology | Volume 37, Issue 12 | First published: 16 June 2025 - Controversies in NEN: An ENETS position statement on the treatment of patients with Grade 3 well-differentiated neuroendocrine tumours of the gastro-enteropancreatic tract
Mairéad G. McNamara, Halfdan Sorbye, Nehara Begum, Emanuel Christ, Nicola Fazio, Lynnette Fernandez-Cuesta, Rocio Garcia-Carbonero, Gregory Kaltsas, Atsuko Kasajima, Ramon Salazar, Ernst Jan M. Speel, Andreas Kjaer
Journal of Neuroendocrinology | Volume 37, Issue 12 | First published: 09 August 2025 - Controversies in NEN: An ENETS position statement on the management of locally advanced neuroendocrine neoplasia of the small intestine and pancreas without distant metastases
M. E. T. Tesselaar, S. Partelli, A. J. A. T. Braat, A. Croitoru, A. P. Soares Santos, J. Schrader, S. Welin, E. Christ, M. Falconi, D. K. Bartsch
Journal of Neuroendocrinology | Volume 37, Issue 12 | First published: 15 September 2025 - Controversies in neuroendocrine neoplasms: An European Neuroendocrine Tumor Society position statement on the role of surgery of the primary tumour in metastatic small intestinal and pancreatic neuroendocrine tumours
Stefano Partelli, Detlef K. Bartsch, Massimo Falconi, Ashley Grossman, Ulrich Knigge, Seppo W. Langer, Wendy Martin, Dermot O'Toole, Aurel Perren, Joerg Schrader, Peter Stalberg, Thomas Walter, Eva Tiensuu Janson
Journal of Neuroendocrinology | Volume 38, Issue 3 | First published: 19 March 2026