5-Fluorouracile Plus Dacarbazine in Metastatic Digestive Neuroendoendocrine Tumors: Efficacy and Potential Biomarkers Abstract #1828

Introduction: The 5-fluorouracile (5FU) + dacarbazine (DTIC) combination has been poorly evaluated in NET
Aim(s): To assess the efficacy and safety of 5FU-DTIC and to explore potential predictive factors of efficacy
Materials and methods: Medical and imaging records of all consecutive patients (pts) with metastatic well-differentiated pancreatic (p) or small intestine (si) NET receiving 5FU-DTIC between 2004 and 2015 in 3 expert centres were retrospectively reviewed. Tumor expression of DAXX, ATRX, MGMT and APNG was centrally performed
Conference: 14th Annual ENETS conference (2017)
Category: Medical treatment – Chemotherapy, medical treatment - others
Presenting Author: Dr Louis de Mestier

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