Blood Gene Transcript Analysis Predicts 68Ga- SSA-PET/CT Imaging in Neuroendocrine Tumors and Defines Disease Status

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Introduction: Limitations of biomarkers and imaging are a concern in the identification of NET status and therapy response.

Aim(s): To identify if circulating molecular markers and imaging provided added value, we assessed the utility of 68Ga-SSA-PET, Ki-67, CgA, and circulating NET transcripts (NETest).

Materials and methods: In two independent datasets (1, pre-PRRT, n=27; 2, follow up, n=22) we evaluated SUVmax, Ki-67, CgA and NETest (regression analyses, generalized linear modeling, ROC analyses).

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Bodei L

Authors: Bodei L, Kidd M, Modlin I, Drozdov I, Prasad V,

Keywords: 68Ga-SSA-PET, NETest, transcripts, PCR,