Abstract Library

#2291 Somatostatin Analogs and mTOR Inhibitors as Radioprotectors or Radiosensitizers in Neuroendocrine Tumor Cells

Introduction: Neuroendocrine tumors (NETs) express somatostatin receptors that are currently utilized for diagnostic and therapeutic approaches. For peptide receptor radionuclide therapy (PRRT), somatostatin analogs are coupled to radionuclides like 90Y or 177Lu, which after injection are bound and taken up specifically by NETs. One hypothesis potentially explaining the discrepancies between expected result and observed outcome of PRRT might be that somatostatin analogs induce a G1 arrest in NET cells, thereby rendering them radioresistant.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Grötzinger C

Authors: Grötzinger C, Exner S, Prasad V, Erdmann S, Wiedenmann B,

Keywords: PRRT,

#2230 Does Somatostatin Receptor (SSR) Positive Tumor Volume Determined on Ga68 DOTANOC PET/CT in Patients with Paraganglioma (PGL)/Pheochromocytoma(PCC) Correlate with Biomarkers? An Explorative Study

Introduction: SSR PET/CT is used in workup of pts with PCC/ PGL. Correlation of tumour burden on PET & biomarkers 24 hr Urine Metanephrines (UMET), normetanephrine (UNMET), UMET:creatinine ratio (MET:Crea),UNMET:creatinine (UNMET:crea) & Chromogranin A (CGA) has not been done.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Steyn R

Authors: Steyn R, Prasad V,

Keywords: 68Ga DOTANOC PET CT, PGL, PCC,

#2225 Long Term Survival after Transplant for Neuroendocrine Liver Metastases: A Case Report and Literature Review

Introduction: Liver transplantation (LT) is offered to selected patients of neuroendocrine tumours (NETs) with unresectable liver metastases (NELM).

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Pande P

Authors: Pande P, Desai G, Shah R, Palepu J,

Keywords: : neuroendocrine tumours, liver metastases, liver transplantation,

#2224 Neuroendocrine Tumours in Tailgut Cysts: A Report of 3 Cases and Review of Literature

Introduction: Retrorectal neuroendocrine tumors (NETs) are rare low grade tumors and their presence in tailgut cyst is rarer.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Pande P

Authors: Pande P, D G, Shah R, Palepu J,

Keywords: presacral neuroendocrine tumours, tailgut cyst, modified Kraske’s approach,

#2223 Diagnostic Dilemma in a Patient with Recurrent Hypoglycaemia: An Unusual Case

Introduction: Recurrent hypoglycemia is a part of Whipple’s triad and usually points towards insulinoma as a cause. Presence of metastasis is uncommon in Insulinoma, and other causes should be ruled out.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Desai G

Authors: Desai G, Pande P, Shah R, Palepu J,

Keywords: proinsulinoma, hypoglycaemia, 213-bismuth prrt,