Abstract Library

#3225 The NETest, a multigenomic liquid biopsy biomarker for neuroendocrine tumor disease, is an accurate diagnostic, predicts surgical recurrence stratifies disease status

Introduction: A universal NET liquid biopsy biomarker is required for optimal management of NET disease.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Modlin I

Authors: Modlin I, Kidd M, Drozdov I, Alexandra K,

Keywords: NETest, biomarker, liquid biopsy, diagnostic,

#1916 Circulating Neuroendocrine Transcripts and Gene Cluster Analysis Predict the Efficacy of PRRT

Introduction: Prediction of PRRT efficacy is critical. We tested a blood-based multigene NET transcript analysis (NETest) to predict efficacy in 2 PRRT-treated NET cohorts. The algorithm comprises >50 genes + clusters of growth factor signaling (GFS) and metabolism (MTB).

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Bodei L

Authors: Bodei L, Kidd M, Singh A, Severi S, Drozdov I,

Keywords: PRRT, efficacy,

#1881 A Gene Expression-Based Nomogram Predicts Progression Free Survival in Small Bowel NETs

Introduction: Nomograms are predictive tools that help prognosticate. A survival nomogram has been validated for small bowel NETs. A circulating NET specific 51gene signature – the NETest – has efficacy (~95%) as a predictor of progression free survival (PFS).

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Kidd M

Authors: Kidd M, Tesselaar M, Korse T, Verbeek W, Drozdov I,

Keywords: Nomogram, prognosis, NETest, PFS, grade, biomarker,

#1879 A Hybrid Clinical Molecular Nomogram Accurately Predicts Survival in PRRT Treated GEP-NETs

Introduction: Clinical assessment has limited prognostic ability. Mathematical tools –nomograms- that incorporate multiple parameters are more effective. Novel transcriptomic data has added value in defining NET biology in tissue and blood. A blood multigene expression analysis test is effective as a molecular prognostic marker for PFS.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Kidd M

Authors: Kidd M, Bodei L, Severi S, Drozdov I, Nicolini S,

Keywords: PRRT, nomogram, NETest, biomarker, OS, PFS, prediction,

#1569 Blood Measurement of NET Transcripts (NETest) Predicts Well-Differentiated Gastroenteropancreatic NET Disease Status and Is Prognostic for Disease Progression

Introduction: A key issue in GEP-NETs is early identification and prediction of disease progression. Clinical evaluation and imaging are limited due to the lack of sensitivity and disease indolence.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Kidd M

Authors: Pavel M, Jann H, Prasad V, Drozdov I, Modlin I,

Keywords: PCR,