#2977
Predicting Survival in Patients with a Neuroendocrine Tumor of the Small Intestine (SI-NET)
Introduction:
SI-NET comprise the largest group of neuroendocrine tumors. Because of their heterogeneity, predicting survival has proven challenging. A nomogram (NG) to assess SI-NET disease specific survival (DSS) has been developed in 2010 by Modlin, et al. based on analysis of retrospective data from the Surveillance, Epidemiology and End Results (SEER) database.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Authors:
Levy S,
van Veenendaal L,
Korse C,
Verbeek W,
Vriens M,
Keywords:
SI-NET,
Nomogram,
Survival,
#1881
A Gene Expression-Based Nomogram Predicts Progression Free Survival in Small Bowel NETs
Introduction:
Nomograms are predictive tools that help prognosticate. A survival nomogram has been validated for small bowel NETs. A circulating NET specific 51gene signature – the NETest – has efficacy (~95%) as a predictor of progression free survival (PFS).
Conference:
14th Annual ENETSConcerence (2017)
Presenting Author:
Kidd M
Authors:
Kidd M,
Tesselaar M,
Korse T,
Verbeek W,
Drozdov I,
Keywords:
Nomogram,
prognosis,
NETest,
PFS,
grade,
biomarker,
#1485
Validation of a Blood Neuroendocrine Tumor Gene Signature, the NETest, in a Netherlands NET Cohort
Introduction:
The CgA has limitations as a monoanalyte biomarker. The introduction of a PCR-based multi-analyte analysis of 51 genes (NETest) has been proposed as more accurate.
Conference:
13th Annual ENETSConcerence (2016)
Presenting Author:
Authors:
Tesselaar M,
Korse T,
Kidd M,
Verbeek W,
Drozdov I,
Keywords:
NETest,
CgA,
PCR,
progressive disease,
#697
Grading NET: Mitosis and Ki-67 conditio sine qua non?
Introduction:
The latest WHO classification for neuroendocrine tumors (NET) defines their grade according to Ki-67 and mitotic index. However, as both parameters are markers for a different part of the cell cycle, their values might not lead to the same grade.
Conference:
10th Annual ENETSConcerence (2013)
Presenting Author:
van Velthuysen M
Authors:
Van Velthuysen M,
Korse T,
Van der Pol A,
Tesselaar M,
Taal B,
Keywords:
grade,
Ki-67,
mitosis,
NET,
