Abstract Library

#2282 Value of Somatostatin Receptor Scintigraphy (SRS) in Patients with Appendiceal Neuroendocrine Neoplasms (ANEN) Based on Clinical Follow-up and Results of NETest

Introduction: Neuroendocrine neoplasms of the appendix (ANEN) are one of the most commonly identified gastroentropancreatic tumours (GEP). The aim of this retrospective study was to review the value of Somatostatin Receptor Scintigraphy (SRS) in staging and imaging follow-up of patients with confirmed ANEN, NENG1 and NENG2 in single institution.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Konsek S, Kolasińska-Ćwikła A, Lewczuk-Myślińska A, Kidd M, Buscombe J,

Keywords: appendiceal neuroendocrine neoplasm, ANEN, somatostatin receptor scintigraphy, SRS, NETest,

#2281 A Novel Classification of Pancreatic Neuroendocrine Tumors (pNETs) Guided by Genomics

Introduction: NET outcomes differ by primary site. Yet pNETs are classified using a generic GI grading system.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Lawrence B

Authors: Lawrence B, Blenkiron C, Parker K, Yeong M, Kramer N,

Keywords: pancreatic NET, genomics,

#2275 Analysis of Gene Expression Patterns of Rectum Neuroendocrine Tumors (NET) Versus Healthy Tissue Reveals Alterations in the MAPK and WNT Signaling Pathways

Introduction: The neuroendocrine tumors (NETs) of the rectum are rare but increasing in incidence, by means of improved endoscopic techniques and histological reporting. They often occur as small polypoid lesions and G1, and in most cases an incidental finding at endoscopy.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Briest F

Authors: Briest F, Hummel M, Grabowski P, Arsenic R,

Keywords: rectum neuroendocrine tumors, NET, MAP kinase, gene expression analysis, Wnt signaling,

#2207 Circulating Neuroendocrine Gene Transcripts (NETest) Decrease Early after Radical Surgery: Preliminary Results of a Prospective Study

Introduction: Specific biomarkers for predicting response and risk of recurrence after surgery for enteropancreatic neuroendocrine tumours (EP-NETs) are still lacking.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Partelli S

Authors: Partelli S, Kidd M, Muffatti F, Andreasi V, Giannone F,

Keywords: NETest, biomarker, Enteropancreatic Neuroendocrine Tumors, diagnosis, surgery,

#1916 Circulating Neuroendocrine Transcripts and Gene Cluster Analysis Predict the Efficacy of PRRT

Introduction: Prediction of PRRT efficacy is critical. We tested a blood-based multigene NET transcript analysis (NETest) to predict efficacy in 2 PRRT-treated NET cohorts. The algorithm comprises >50 genes + clusters of growth factor signaling (GFS) and metabolism (MTB).

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Bodei L

Authors: Bodei L, Kidd M, Singh A, Severi S, Drozdov I,

Keywords: PRRT, efficacy,