Abstract Library

#4444 Digestive neuroendocrine tumour diagnosis and therapeutic particularities: Experience of medical oncology centre Annaba, Algeria

Introduction: Neuroendocrine digestive tumours are increasingly diagnosed as a result of the rise in radiological and endoscopic procedures, improved pathological classification, and likely an increase in true incidence. All patient files must be discussed in RCP.

Conference:

Presenting Author:

Authors: Bechairia W, Djedi H,

Keywords: neuroendocrine digestive tumour, late diagnosis, multidisciplinary care,

#4418 Endoscopic ultrasound-guided radiofrequency ablation is a safe and efficient treatment of symptomatic insulinomas – A single centre experience of 14 patients

Introduction: The vast majority of insulinomas are benign and less than 20 mm. Surgery is considered as standard treatment, but complications are significant. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) represents a novel and minimally invasive approach.

Conference:

Presenting Author: Andreassen M

Authors: Andreassen M, Kovacevic B, Brink L, Hansen C, Knigge U,

Keywords: Insulinoma, Benign, EUS, radiofrequency ablation,

#4338 Spot urine 5-HIAA creatinine ratio is comparable to 24hr urine collection for diagnosis of carcinoid syndrome

Introduction: Carcinoid syndrome (CS) constitutes up to 20% of functional neuroendocrine neoplasms and can lead to carcinoid crisis (CC), a potentially fatal complication during invasive procedures. Urine 5-hydroxyindoleacetic acid (5HIAA) is the preferred diagnostic biomarker for CS and prognostic marker for CC. 5HIAA is collected over 24-hours with strict dietary restriction for the 2 days prior as well as the day of the collection. False positive and negative results can occur due to under and over-collection. Patient inconvenience also contributes to the low request rate of this test.

Conference:

Presenting Author: Kong G

Authors: Chiang C, Gamage I, Del Olmo-Garcia M, Pasanen L, Wong H,

Keywords: carcinoid syndrome, carcinoid crisis, urine 5-HIAA, biomarker,

#4240 Plasma extracellular vesicles number and size distinguish patients with neuroendocrine neoplasms

Introduction: Neuroendocrine Neoplasms (NENs) are heterogeneous neoplasms, whose metastatic potential is challenging to predict. Extracellular vesicles (EVs) have been described as mediators of communication between the tumor cells and their microenvironment, driving the formation of metastatic niches.

Conference:

Presenting Author: Angelioudaki I

Authors: Angelioudaki I, Pantazatou V, Tzingounis A, Kataki A, Memos N,

Keywords: Extracellular vesicles, plasma, Gastroenteropancreatic NEN,

#4026 Neuroendocrine tumors in the stomach: An epidemiological analysis of Belgian Cancer Registry data

Introduction: GEP-NEN are rare and heterogeneous tumors including NET, NEC and MiNEN. NET are classified based on mitotic activity and Ki-67 index (G1, 2 and 3), NEC are always high grade (G3). Gastric NEN should be clinically subtyped as this has therapeutic implications (type 1, 2 and 3).

Conference:

Presenting Author:

Authors: Maly M, Callebout E, Hoorens A, Ribeiro S, Geboes K,

Keywords: neuroendocrine, stomach, neoplasm, epidemiology,