Endoscopic Ultrasound-Guided Fine Needle Tissue Acquisition (EUS-FNTA) Using a 19-G Needle for Histological Grading of Pancreatic Endocrine Tumors (PETs): A Prospective Study

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Introduction: EUS-FNTA is increasingly used in the diagnosis of pancreatic endocrine tumors (PETs). Ki-67 expression, an important prognostic factor according to the WHO classification, is difficult to be determined on cytological specimens.

Aim(s): We prospectively evaluated the feasibility and yield of EUS-FNTA to obtain tissue samples for histological diagnosis and Ki-67 expression in patients with suspected PETs.

Materials and methods: Twenty-five consecutive patients with suspicious PETs underwent, between August 2009 and September 2010, EUS-FNTA using a 19G needle. The collected specimens were placed directly in formalin for histological examination. Overall, EUS-FNTA could be performed in all patients without complications.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Larghi A, Fusco A, Bianchi A, Lugli F, Iacovazzo D,

Keywords: EUS, Ki-67, grading, pancreas,