Abstract Library

#2737 Identification of a Novel MAFA Missense Mutation Causing Familial Insulinomatosis

Introduction: Insulinomatosis is a rare pancreatic disease characterized by an adult-onset condition of recurrent hyperinsulinemic hypoglycemia caused by multiple insulin-secreting neuroendocrine tumors.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Fottner C

Authors: Fottner C, Sollfrank S, Ghiasi M, Ferrata M, Schad A,

Keywords: Insulinomatosis, Insulinoma, hyperinsulinemic hypoglycemia, MAFA,

#1207 A Novel MEN1 Gene Variant in a Sporadic Case of Multiple Endocrine Neoplasia Type 1

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by the occurrence of hyperparathyroidism, pituitary adenomas and duodeno-pancreatic neuroendocrine tumours (NETs). Germline mutations of the MEN1 gene are identified in up to 87% of MEN1 families and 82% of isolated MEN1 cases.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Iacovazzo D

Authors: Iacovazzo D, Piacentini S, Lugli F, Bianchi A, Gabrovska P,

Keywords: MEN1, mutation, gastric carcinoid,

#1206 Two Cases of Ectopic ACTH-Secreting Neoplasm of Occult Origin Becoming Overt After Bilateral Adrenalectomy

Introduction: Cushing's syndrome (CS) is an endocrine disorder associated with serious consequences if not adequately treated. Nearly 80% of the cases of endogenous hypercortisolism are adrenocorticotropic hormone (ACTH) dependent, the ACTH source being pituitary in about 70-80% and ectopic in 10-15%. The ACTH source may remain occult in few cases for many years in spite of extensive investigations.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Piacentini S, Iacovazzo D, Lugli F, Giampietro A, Bianchi A,

Keywords: Cushing's syndrome, Ectopic ACTH, Bilateral adrenalectomy,

#1013 Evaluation of VEGF and Endocan/ESM-1 Expression in pNETs and Correlation with Ki-67 and Prognosis

Introduction: Endocan has been reported as specific of endothelial tumor cells and was shown to be expressed by tip cells during the angiogenesis process.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Lugli F

Authors: Lugli F, Iacovazzo D, Lanza P, Inzani F, De Waure C,

Keywords: GEP-NET, Endocan, VEGF,

#1012 Efficacy of Lanreotide Autogel in MEN1-Related Gastrinoma: A Case Series

Introduction: GEP NETs, especially gastrinomas, occur in 40-70% of MEN1 patients and represent the main cause of death in these patients.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Iacovazzo D

Authors: Iacovazzo D, Lugli F, Bianchi A, Capoluongo E, Lucci-Cordisco E,

Keywords: MEN1, SSA, gastrin,