Abstract Library

#2793 A Phase II, Open-Label, Multicenter Trial of Avelumab in Patients with Advanced, Metastatic High Grade Neuroendocrine Carcinomas NEC G3 (WHO 2010) Progressive after First-line Chemotherapy (AVENEC)

Introduction: High grade Neuroendocrine Neoplasias (NEN) are rare tumors with a poor prognosis and no established second line therapy.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Weber M

Authors: Fottner C, Apostolidis L, Ferrata M, Krug S, Michl P,

Keywords: NEC, NEN G3, check-point inhibitor, Avelumab, anti-PD-L1-antibody, immunotherapy,

#2737 Identification of a Novel MAFA Missense Mutation Causing Familial Insulinomatosis

Introduction: Insulinomatosis is a rare pancreatic disease characterized by an adult-onset condition of recurrent hyperinsulinemic hypoglycemia caused by multiple insulin-secreting neuroendocrine tumors.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Fottner C

Authors: Fottner C, Sollfrank S, Ghiasi M, Ferrata M, Schad A,

Keywords: Insulinomatosis, Insulinoma, hyperinsulinemic hypoglycemia, MAFA,

#968 An Early Rare MEN1 Phenotype

Introduction: A 13-yr-old boy was referred to our department for short stature.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Battocchio M, Martini C, Rebellato A, Ferrata M, Zanchetta E,

Keywords: MEN1, hypercorticism,

#958 Hypoglycemic Syndrome Recurrence after Surgical Removal of a Pancreatic Neuroendocrine Adenoma

Introduction: A 56-year-old woman was submitted to caudal pancreatectomy for an insulin-secreting adenoma suspected by MRI and fast test positivity at 38th hour. Intraoperative US excluded other pancreatic lesions but tissue analysis described a 8mm neuroendocrine well-differentiated tumor and the surrounding pancreatic tissue exhibited characteristics of nesidioblastosis. Five months after surgery, she still reported episodes of hypoglycemia requiring diazoxide therapy and she was admitted to our department.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: De Carlo E

Authors: Bettini V, Martini C, Ferrata M, Battocchio M, Zanchetta E,

Keywords: insulinoma, nesidiblastosis, hypoglycemia,