Abstract Library

#3947 Heterogeneity of multiple pancreatic neuroendocrine tumors identified by 68Ga-DOTANOC and 68Ga-exendin-4 PET/CT in a patient with endogenous hyperinsulinemic hypoglycaemia and multiple endocrine neoplasia 1

Introduction: Insulinomas are the most frequent functional neuroendocrine tumors of pancreas cause endogenous hyperinsulinemic hypoglycemia (EHH). In about 10% cases, insulinomas are associated with multiple endocrine neoplasia 1 (MEN1).

Conference:

Presenting Author: Xu J

Authors: Xu X, Xu X, Liang Y, Zhang M, Chen J,

Keywords: MEN1, insulinoma, 68Ga-DOTANOC, 68Ga-exendin-4, PET/CT,

#3324 Elastographic localization of insulinoma

Introduction: A 15-year-old healthy female, initially admitted with less serious signs of hypoglycemia. Laboratory studies showed a glucose concentration of 1.2 mmol/l and insulin 9.6 μU/ml. Complete blood count, basal metabolic profile, activity of C - reactive protein and urine drug screen, were unremarkable. Fasting test confirmed biochemical signs of insulinoma.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Uhrík P

Authors: Uhrík P, Nosakova L, Pindura M, Bánovčin P, Hyrdel R,

Keywords: insulinoma, endosonography, elastography,

#3187 Primary insulinoma of the liver

Introduction: Insulinoma is a moderately rare neuroendocrine tumor which is normally located in the pancreas. There are extremely rare cases of metastatic insulinoma. We present the case of the primary insulinoma of the liver which was successfully surgical treated.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Kaldarov A

Authors: Kaldarov A, Kriger A, Gorin D, Berelavichus S, Galkin G,

Keywords: insulinoma, liver, neuroendocrine tumor, hypoglycemia, hyperinsulinism,

#3145 Reduction of serum insulin levels and diazoxide doses as an effect of PRRT in patients with severe hypoglycemia due to primary non-operative insulinoma

Introduction: Severe hypoglycaemia in a course of inoperable insulinoma may be life-threating and it is not always well controlled even by high doses of diazoxide, which in some cases cause a significant toxicity. Nowadays, other forms of effective therapy are not available - use of protein kinase inhibitors (everolimus, sunitynib) sometimes bring satisfactory effect but is often associated with the risk of serious side effects. Use of Peptide receptor radionuclide therapy (PRRT), characterized by relatively low toxicity, is not widely used.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Opalińska M

Authors: Opalinska M, Sowa-Staszczak A, Al Maraih I, Kostecka-Matyja M, Hubalewska-Dydejczyk A,

Keywords: PRRT, insulinoma, NEN,

#3123 Arterial calcium-stimulated venous sampling to reveal insulinoma in case of pancreatic multiple neuroendocrine neoplasms

Introduction: Insulinoma is a functioning pancreatic neuroendocrine tumor (pNET) that produces insulin and causes clinical symptoms of severe hypoglycemia. The arterial calcium stimulation with hepatic venous sampling (ASVS) can localize the insulin-producing tumor and help to avoid the excessive volume of surgery in case of multiple pancreatic neuroendocrine tumors.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Kaldarov A

Authors: Kaldarov A, Panteleev V, Varava A, Raevskaya M, Davidenko P,

Keywords: insulinoma, neuroendocrine tumor, neuroendocrine neoplasm, pancreas, arterial calcium stimulation with hepatic venous sampling, ASVS, parenchyma-sparing surgery,