Evaluation of VEGF and Endocan/ESM-1 Expression in pNETs and Correlation with Ki-67 and Prognosis

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Introduction: Endocan has been reported as specific of endothelial tumor cells and was shown to be expressed by tip cells during the angiogenesis process.

Aim(s): The assessment of immunohistochemical VEGF and Endocan expression in functioning and non-functioning pNETs and the comparison of these markers with clinical features, Ki-67 and TNM staging.

Materials and methods: We collected a total number of 79 pNET surgical specimens for immunohistochemestry (IHC). The population chosen was classified according to type of diagnosis, sex, age, grading and staging.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Lugli F

Authors: Lugli F, Iacovazzo D, Lanza P, Inzani F, De Waure C,

Keywords: GEP-NET, Endocan, VEGF,