Abstract Library

#4340 Predominant volumetric phenotype in dual PET and overall survival in NENs

Introduction: Dual 18F-FDG/68Ga-DOTATATE PET can predict NEN prognosis and guide treatment choice. However, research to date (such as the NEPTET score) has focused on the dual PET phenotype of single-point lesions rather than of the total disease volume.

Conference:

Presenting Author: Chan D

Authors: Chan D, Bernard E, Mokhtar S, Chou A, Gill A,

Keywords: Prognostic biomarker, PET/CT, tumour volume, 18F-FDG, 68Ga-DOTATATE,

#4339 Dual threshold contouring for [68Ga]DOTATATE PET and correlation with overall survival (OS) in patients with neuroendocrine neoplasia (NEN)

Introduction: Accurate contouring for [68Ga]DOTATATE PET in NEN is challenging due to differing physiological uptake for the liver, spleen and other organs. This poses a significant problem for absolute thresholding algorithms using a single threshold, even if the threshold is based on liver uptake (as suggested for FDG PET by PERCIST). Improved contouring of PET to measure [68Ga]DOTATATE-avid tumour volume could help clinical translation of this potential biomarker.

Conference:

Presenting Author: Chan D

Authors: Chan D, Mokhtar S, Bernard E, Diakos C, Sabahi Z,

Keywords: prognostic biomarker, PET imaging, [68Ga]DOTATATE, Total Lesion Volume,

#3656 Glucagonomas – Characteristics and treatment options based on a French multicenter cohort study

Introduction: Glucagonoma is a rare functional pancreatic neuroendocrine tumor (pNET).

Conference:

Presenting Author:

Authors: Perrier M, Brugel M, Walter T, Goichot B, Lièvre A,

Keywords: glucagonoma, neuroendocrine neoplasm, pancreas, necrolytic migratory erythema,

#3168 Endocrine neoplasias and non-endocrine neoplasias associated with primary aldosteronism

Introduction: Primary aldosteronism (PA) is the main cause of secondary arterial hypertension (AH) of endocrine origin (1). Clinical presentation may include resistance to treatment for AH, hypokalemia, with the autonomous secretion of aldosterone. Somatic mutations and epigenetic factors are the most frequent etiologies (2). Adrenal tumors may be a characteristic of MEN1 syndrome (3). Some case reports have associated endocrine neoplasms with PA; however, the real prevalence of this association is unknown (3).

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Huertas Gnecco B

Authors: Huertas Gnecco B, González Devia D, Jaramillo Chacón H, López Panqueva R, Cañón Solano D,

Keywords: primary hyperaldosteronism, primary aldosteronism, neuroendocrine tumor, endocrine tumor, neoplasia,

#3074 Medullary Thyroid Carcinoma and DIPNECH: An Unexpected Association

Introduction: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumour of the C-cells of thyroid gland. Diffuse idiopathic pulmonary neuroendocrine cells hyperplasia (DIPNECH) is a rare condition, thought to be primarily a neuroendocrine proliferative process which can develop into carcinoid tumours.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Lima Ferreira J, Marques B, Elvas A, Simões de Carvalho F, Fonseca A,

Keywords: medullary thyroid cancer, DIPNECH, neuroendocrine tumour, carcinoid tumour, pulmonary nodules,