Abstract Library

#4471 Acromegaly and small intestinal neuroendocrine tumours: Association or coincidence?

Introduction: Neuroendocrine tumours of the small intestine (SI-NETs), although rare, are the most prevalent primary neoplasms of this organ. Acromegaly is characterised by excessive secretion of growth hormone (GH), typically due to a pituitary adenoma, but in rare cases, it can result from ectopic secretion of GH-releasing hormone (GHRH) by non-pituitary tumours, particularly NETs of the lung or pancreas.

Conference:

Presenting Author: G. Martins R

Authors: Martins Fernandes A, Silva L, Serranito M, Elvas A, Santos J,

Keywords: neuroendocrine tumour, small intestinal neuroendocrine tumour, acromegaly,

#3572 Capecitabine and temozolomide in advanced neuroendocrine neoplasms – A single center experience

Introduction: Neuroendocrine neoplasms (NENs) are heterogeneous malignancies, with a great variability in clinical behaviour and prognosis. Capecitabine and temozolomide combination (CAPTEM) has shown positive results in these patients, with a good safety profile.

Conference:

Presenting Author:

Authors: Monteiro J, Caetano A, Pires M, Costa C, Elvas A,

Keywords: neuroendocrine neoplasm, neuroendocrine tumor, treatment, capecitabine, temozolomide, capecitabine and temozolomide, CAPTEM,

#3570 Metastatic middle ear neuroendocrine tumor treated with Somatostatin analogues and PRRT – A case report

Introduction: Neuroendocrine adenomas of the middle ear (NEAME) are rare tumors. They have mostly indolent biological behaviour, however, reports of an aggressive course and metastasis have been described.

Conference:

Presenting Author: Gomes Martins R

Authors: Elvas A, Magalhães J, Monteiro J, Barros J, Rei L,

Keywords: Neuroendocrine adenomas of the middle ear, somatostatin analogues, peptide receptor radionuclide therapy,

#3565 Grade 3 neuroendocrine neoplasms – Real life experience and prognostic biomarkers

Introduction: Grade 3 neuroendocrine neoplasms (G3 NEN) are a heterogeneous group, including well differentiated tumors (NET) and poorly differentiated carcinomas (NEC), whose identification can be challenging. Accessible prognostic tools are needed to individualize treatment. Data suggests neutrophil/lymphocyte ratios (NLR) and systemic inflammatory index (SII) have prognostic value in NEN.

Conference:

Presenting Author: Rebordão Pires M

Authors: Rebordão Pires M, Monteiro J, Amorim Costa C, Caetano A, Elvas A,

Keywords: Grade 3 neuroendocrine neoplasm, NEC, NET, Neutrophil to lymphocyte ratio, Systemic Inflammatory Index, Ki67, Prognostic biomarker,

#3564 Prevalence of other malignant cancers in patients with neuroendocrine neoplasms

Introduction: Neuroendocrine neoplasms (NNE) are a heterogeneous group, arising from different anatomical locations. Studies showed a higher prevalence of other malignancies associated with NNE when compared to other types of cancer.

Conference:

Presenting Author: Amorim Costa C

Authors: Amorim Costa C, Peixoto M, Rebordão Pires M, Cruz Monteiro J, Elvas A,

Keywords: Neuroendocrine neoplasm, solid malignancies, hematological malignancies, screening,