Abstract Library
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#4230 Grade ≥3 subacute haematological toxicity with 177Lu-DOTATATE PRRT – Results from LUMEN study
Introduction: Bone marrow toxicity during peptide receptor radionuclide therapy (PRRT), results from radiation damage to haematopoietic tissue. Prospective comprehensive data on subacute haematological toxicity are scarce.
Conference:
Presenting Author: Mileva M
Authors: Mileva M, van Bogaert C, Ameye L, Flamen P, Karfis I,
Keywords: peptide receptor radionuclide therapy, GEP-NET, haematological toxicity,
Introduction: 177Lu-DOTATATE (PRRT) treatment is indicated in Spain in GEPNET but its activity in other somatostatin receptor-positive tumors is known.
Conference:
Presenting Author: Jimenez-Fonseca P
Authors: Jimenez-Fonseca P, Pubul V, Belló P, Riesco-Martinez M, Aller J,
Keywords: PRRT, NET, Somatostatin receptor-positive tumor, Survival,
Introduction: There are concerns for the risk of IO in patients with GEPNETs, especially in cases with peritoneal metastases or mesenteric vascular encasement.
Conference: 18th Annual ENETS Concerence (2021)
Presenting Author: Badawy M
Authors: Badawy M, Hobday T, Johnson G, Halfdanarson T, Young J,
Keywords: gastrointestinal NETs, PRRT (Lu-DOTATATE), intestinal obstruction, overall survival,
Introduction: Assessment of disease status remains the fundamental basis in the management of gastro-entero-pancreatic neuro-endocrine tumors (GEPNETs). Circulating molecular information might be used as a liquid biopsy to predict its clinical course.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: van Treijen M
Authors: van Treijen M, van der Zee D, Heeres B, Staal F, Vriens M,
Keywords: biomarker, progression-free survival, gastro-entero-pancreatic neuroendocrine tumours,
Introduction: PRRT with 177Lu-DOTATATE (LuTate) is an effective treatment option in patients with metastatic or inoperable GEP-NETs.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: van der Zwan W
Authors: Van der Zwan W, Wyld D, Brabander T, Teunissen J, Kam B,
Keywords: PRRT, 177Lu-DOTATATE, Capecitabine, Xeloda, PFS, OS, Toxicity, GEP-NET, RCT, Randomized,