Clinical Nomogram Development and Predictive Utility for Appendiceal and Colorectal NETs

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Introduction: Nomograms are predictive tools that help prognosticate. A survival nomogram has been validated for small bowel NETs has been adapted for other sites. About 50% of NETs occur in the appendix-colon-rectum. Locations have widely differing outcomes (survival 50-100%).

Aim(s): Develop individual clinical-based survival nomograms for NETs of the appendix, cecum, ascending colon (AC), sigmoid and transverse colon (STC) and rectum.

Materials and methods: Clinical history including age, gender, grade (NETG1, G2 or NET/NECG3), stage (CSI-IV), tumor size, and secretory status were assessed for appendix (n=99); cecum (n=40); AC (n=16), STC (n=23) and rectum (n=99). Uni- and multivariate analyses identified clinically relevant factors. Cox-proportional modeled hazard ratios to develop scores and generate nomograms. Median OS and accuracy for predicting survival were measured.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Kidd M

Authors: Kolasińska-Ćwikła A, Ćwikła J, Kidd M, Bodei L, Lewczuk A,

Keywords: Nomogram,