Survival Analysis after i.a. 90Y-DOTATATE PRRT, in Patients with Non-Resectable, Advanced, Progressive, Liver-Dominant Neuroendocrine Neoplasms Abstract #1894

Introduction: A
Aim(s): To assess long-term survival in non-resectable, progressive, liver-dominant GEP-NEN after intraarterial (i.a.) 90Y DOTATATE peptide receptor radionuclide therapy-PRRT
Materials and methods: 22 subjects, 12 female, mean age 56.2. Histological proven G1/G2/G3: 4/17/1; secretor 10 pts (46%). Documented progression DP: 100% (RECIST, clinical or biochemical in case or secretor tumors) with relapse on previous therapy. Overall 56 i.a. 90Y-DOTATATE sessions. Initial tumor responses assessed, 6wks after PRRT and then 3mo intervals of follow-up. Objective tumor response was classified according to RECIST 1.0, initially 6wks and then after each of the 6mo. OS and PFS were evaluated using Kaplan Meier methods
Conference: 14th Annual ENETS conference (2017)
Category: PRRT-Ablative therapies- Endoscopic treatment, surgical treatment
Presenting Author: MD, PhD Miroslaw L Nowicki

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