Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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Participants of the 2025 ENETS Conference enjoy full access to the 2025 conference digital resources through myENETS: the abstract booklet, e-posters and videos, slide decks of talks, the poster carousel, and more.

ENETS Abstract Search

#3196 Phase 2 study of cisplatin and everolimus in patients with metastatic extrapulmonary neuroendocrine carcinoma (NEC)

Introduction: Extrapulmonary NEC (EP-NEC) are an aggressive subgroup of neuroendocrine neoplasms (NEN). Advanced EP-NEC are generally treated with platinum-based cytotoxic regimens. Although highly responsive to cytotoxic therapies, recurrence occurs frequently and rapidly, with a poor prognosis and lack of further treatment options. Genetic alterations in the mTOR pathway have been identified in NEN, providing a rationale for treatment with the mTOR inhibitor everolimus.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Levy S

Authors: Levy S, Verbeek W, Eskens F, de Groot D, Van Leerdam M,

Keywords: phase 2, extrapulmonary NEC, everolimus, cisplatin,

#2796 Avelumab for Advanced Merkel Cell Carcinoma in the Netherlands; A Nationwide Survey

Introduction: Merkel cell carcinoma (MCC) is a rare, tumor of the skin associated with high recurrence rates and poor survival. Clinical trials have shown activity of checkpoint inhibitors targeting programmed death-(ligand)-1 (PD-(L)1). Avelumab is the only PD-L1 inhibitor that has been approved in the Netherlands for advanced/metastatic MCC (mMCC).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Levy S

Authors: Levy S, Aarts M, Eskens F, Keymeulen K, Been L,

Keywords: Merkel Cell Carcinoma, Avelumab, PD-L1,