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#220 The Global mTOR Inhibitor Torin1 is More Effective than the mTORC1 Inhibitor, Everolimus, Alone or in Combination with Histone Deacetylases Inhibitors, in Suppressing Neuroendocrine Tumors Cell Proliferation

Introduction: Torin1, a new mTOR inhibitor that globally inhibits both mTORC1 and mTORC2, seems to impair cell growth and proliferation to a greater degree than rapamycin; its effects in NET cells are unknown.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Grozinsky-Glasberg S, Rubinfeld H, Cohen O, Greif F, Kammer A,

Keywords: Torin1, RAD001, NETs, antiproliferation, Akt, mTOR, HDACi,