Abstract Library

#4065 DAREON™-7: A Phase I, open-label, dose escalation and expansion cohort trial of the delta-like ligand (DLL3)-targeting T-cell engager BI 764532, plus first-line platinum-based chemotherapy in patients with DLL3-positive neuroendocrine carcinomas

Introduction: Neuroendocrine carcinomas (NEC) have limited treatment options. DLL3 is highly expressed on NEC and is a promising treatment target. In an ongoing Phase I trial (NCT04429087), BI 764532, a DLL3/CD3 IgG-like T-cell engager (TcE), was tolerable with promising activity in pretreated pts with DLL3-positive (+) tumours, including NEC.

Conference:

Presenting Author: Capdevila J

Authors: Capdevila J, Vandamme T, Niccoli P, Mishima S, Kato K,

Keywords: neuroendocrine carcinoma, delta-like ligand, T-cell engager, Phase I,

#3561 Minimally invasive laparoscopic and robotic versus open hepatic resection for NEN liver metastasis: Case matched study with propensity score matching

Introduction: Minimally invasive surgery has been widely considered as feasible and safe option in liver resection. However, little is known about the impact in the surgical therapy of NEN liver metastasis.

Conference:

Presenting Author: Pascher A

Authors: Pascher A, Morguel H, Katou S, Struecker B,

Keywords: neuroendocrine liver metastasis, liver surgery,

#2184 4D Ultrasound High Definition Flow with Spatio-Temporal Image Correlation in Evaluation of Neuroendocrine Liver Metastases – Preliminary Study

Introduction: 4D Ultrasound technology merging Power Doppler option called High Definition Flow (HDF) with Spatio-Temporal Image Correlation (STIC) is used in gynecology and obstetrics. It seems to be a promising tool in assessing tissue vascularization.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Janas K, Kudła M, Janas A, Blicharz-Dorniak J, Kos-Kudła B,

Keywords: nens, metastasis, hdf, stic, 4-dimensional sonography,

#1887 Neuroendocrine Neoplasm Registry: Single-Centre Experience and Outcomes

Introduction: Neuroendocrine neoplasm (NEN) registries are highly needed to investigate epidemiology of NEN, collect and deliver data on efficacy of management strategies in NEN and improve quality of NEN pts care.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Rosiek V, Strzelczyk J, Zemczak A, Kos-Kudła B,

Keywords: NEN, single-centre registry,

#531 Long-Term Outcomes in 50 Consecutive Patients with Neuroendocrine Tumors of the Pancreas

Introduction: Recently, the new World Health Organization (WHO) classification and TNM staging for neuroendocrine tumors of the pancreas (pNETs) were published.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Natori T, Katori M, Seki M,

Keywords: neuroendocrine tumors of the pancreas, surgery, WHO classification, TNM staging,