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#1572 Study of the Biological Significance of the IGF-IEc (MGF) in Well and Poorly Differentiated Neuroendocrine Neoplasms

Introduction: Insulin-like growth factor-I (IGF-I) has a key role in cell proliferation, differentiation, migration, and survival. Different IGF-I mRNA transcripts, such as IGF-IEc (mechano growth factor, MGF), are produced by alternative splicing. MGF has been implicated in muscle regeneration process as well as in the pathophysiology of various types of cancer.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Alexandraki K

Authors: Alexandraki K, Philippou A, Boutzios G, Theohari I, Moschouris P,

Keywords: Neuroendocrine neoplasms, MGF, IGF-IEc, ki-67,