Abstract Library

#3028 Pancreatic Neuroendocrine Neoplasms: Dissecting the Molecular Heterogeneity

Introduction: Pancreatic neuroendocrine neoplasms (PNENs) are a group of rare but biologically and clinically heterogeneous neoplasms with variable patient outcomes. Little is known about the molecular differences between PNENs and the biologic significance of such divergence.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Yang K, Kalloger S, Aird J, Lee M, Colborne S,

Keywords: Pancreatic neuroendocrine neoplasms, Exome, Transcriptome, Proteome,

#2999 Aberrant Tryptophan Metabolism in Stromal Cells Is Associated with Mesenteric Fibrosis in Small Intestinal Neuroendocrine Tumours

Introduction: Increased levels of serotonin secretion are associated with mesenteric fibrosis (MF) in small intestinal neuroendocrine tumors (SI-NETs). However, only a proportion of patients with increased serotonin production will develop mesenteric fibrosis.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Blazevic A

Authors: Blazevic A, Iyer A, Van Velthuysen M, Hofland J, Franssen G,

Keywords: Small-intestinal neuroendocrine tumors, mesenteric fibrosis, serotonin, tryptophan metabolism, proteomics,

#2931 One-Stage Middle-Preserving Pancreatectomy: Indications and Outcomes

Introduction: Parenchyma-sparing surgical techniques are used in pancreatic surgery to preserve organ function. Middle-preserving pancreatectomy (MPP) may be an alternative to total pancreatectomy (TP) in benign/borderline disease that does not affect pancreatic body.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Milanetto A, David A, Fassan M, Pasquali C,

Keywords: one-stage middle preserving pancreatectomy, parenchyma-sparing pancreatic surgery,

#2911 Pancreatic Neuroendocrine Neoplasms and GastroIntestinal Stromal Tumours: A Single-Institution Experience of a Rare Association and Review of the Literature

Introduction: Pancreatic neuroendocrine neoplasms (pNENs) and gastrointestinal stromal tumours (GISTs) are both rare neoplasms, and they have an estimated incidence of about 1/100,000 per year and about 1-1.5/100,000 per year, respectively.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Milanetto A, Pacciani S, Da Broi M, Gais Zürcher A, Fassan M,

Keywords: pancreatic neuroendocrine neoplasm, gastrointestinal stromal tumour, pancreatic surgery,

#2909 Serotonin-Secreting NeuroEndocrine Neoplasms of the Pancreas: Which Are the Primary Pancreatic Carcinoids?

Introduction: Serotonin-secreting pancreatic neuroendocrine neoplasms (5-HT-secreting pNENs) are very rare. They are characterised by high urinary 5-hydroxyindole-acetic acid (5-HIAA) levels (or high serum 5-HT levels).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Milanetto A, Fassan M, Gais Zürcher A, David A, Pasquali C,

Keywords: Pancreatic neuroendocrine neoplasm, primary pancreatic carcinoid, serotonin-secreting pancreatic tumour, serotonin-producing pancreatic tumour,