Pancreatic Neuroendocrine Neoplasms and GastroIntestinal Stromal Tumours: A Single-Institution Experience of a Rare Association and Review of the Literature


Introduction: Pancreatic neuroendocrine neoplasms (pNENs) and gastrointestinal stromal tumours (GISTs) are both rare neoplasms, and they have an estimated incidence of about 1/100,000 per year and about 1-1.5/100,000 per year, respectively.

Aim(s): To evaluate non-syndromic cases of pNENs associated with a synchronous GIST, and to perform a review of the literature on this uncommon association.

Materials and methods: We evaluated clinic-pathological features, post-operative outcome and follow-up of patients who underwent surgery for non-syndromic synchronous pNENs and GISTs in our unit (2003-2017).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Milanetto A, Pacciani S, Da Broi M, Gais Zürcher A, Fassan M,

Keywords: pancreatic neuroendocrine neoplasm, gastrointestinal stromal tumour, pancreatic surgery,

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