Serotonin-Secreting NeuroEndocrine Neoplasms of the Pancreas: Which Are the Primary Pancreatic Carcinoids?


Introduction: Serotonin-secreting pancreatic neuroendocrine neoplasms (5-HT-secreting pNENs) are very rare. They are characterised by high urinary 5-hydroxyindole-acetic acid (5-HIAA) levels (or high serum 5-HT levels).

Aim(s): To evaluate clinic-pathological features, treatment and prognosis of 5-HT-secreting pNENs patients.

Materials and methods: Patients with a 5-HT-secreting pNEN observed in our unit (1986-2015) were included. Diagnosis was based on high urinary 5-HIAA levels and/or high serum 5-HT levels. Follow-up (FU) to December 2018.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Milanetto A, Fassan M, Gais Zürcher A, David A, Pasquali C,

Keywords: Pancreatic neuroendocrine neoplasm, primary pancreatic carcinoid, serotonin-secreting pancreatic tumour, serotonin-producing pancreatic tumour,

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