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#2804 Claudin-18 Is a Sensitive and a Specific Marker for Gastric Neuroendocrine Tumors

Introduction: Antibody-based cancer therapies are emerging as promising therapeutics in oncology, including one in clinical trials that targets claudin-18, a protein expressed in normal gastric epithelium and some gastric adenocarcinoma. We currently have no markers for gastric well-differentiated neuroendocrine tumors (NETs).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Wong M, Huynh C, Kim S, Dhall D, Guindi M,

Keywords: claudin-18, anti-claudin 18, neuroendocrine tumor, neuroendocrine hyperplasia, autoimmune metaplastic atrophic gastritis,