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#820 ACTG2 Inhibits Growth and Is Epigenetically Repressed in Small Intestinal Neuroendocrine Tumors

Introduction: Small intestinal neuroendocrine tumors (SI-NETs) originate from the enterochromaffin cells in the ileum. Actin gamma smooth muscle 2 (ACTG2) is downregulated in lymph node metastases from SI-NETs. ACTG2 and microRNA-145 (miR-145) are aberrantly expressed in other cancers and ACTG2 can be induced by miRNA-145.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Edfeldt K, Hellman P, Westin G, Stålberg P,

Keywords: SI-NET, ACTG2, miR-145, epigenetics,