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#357 Alternative Splicing and Differential Gene Expression in Pancreatic NETs

Introduction: Alternative splicing is an important mechanism to increase diversity of the proteome in higher organisms. These protein isoforms can provide as a selective drug target or marker for cancer diagnosis. We present here a new DNA array that allows identification of splice variation and differential expression of 357 G protein-coupled receptors (GPCR) and 11 proteins of the extracellular matrix.

Conference:

Presenting Author:

Authors: Körner J, Wiedenmann B, Grötzinger C,

Keywords: splice variants array,