Added value of multifrequency magnetic resonance elastography in predicting pathological grading of pancreatic neuroendocrine neoplasms

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Introduction: The mechanical properties of tumour tissues offer a new side for disease diagnosis.

Aim(s): To prospectively investigate the pancreatic stiffness (c) and fluidity (φ) of pancreatic neuroendocrine neoplasms (pNENs), measured using multifrequency magnetic resonance elastography (MRE), and evaluate their performance in predicting pNENs pathological grade.

Materials and methods: This study included 96 untreated patients with pathologically confirmed pNENs who underwent multifrequency MRE within 2 weeks before surgery between September 2021 and November 2023. Independent predictors of pathological grade were identified using the multivariate regression analysis, and predictive performance was assessed using receiver operating characteristic curves.

Conference:

Presenting Author: Liu J

Authors: Liu J, Yuan J, Wen T, Wang L, Peng Z,

Keywords: magnetic resonance elastography, pancreatic neoplasm, carcinoma, neuroendocrine, pathological grade,