Analysis of the efficacy of STEM chemotherapy in patients with metastatic paraganglioma

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Introduction: Paraganglioma is a special kind of neuroendocrine tumor, located outside the adrenal gland, about 35-40% is related to heredity and has corresponding germline mutation. The therapeutic response is different from that of neuroendocrine tumors derived from gastrointestinal and pancreas.

Aim(s): To analyse the efficacy and safety of STEM chemotherapy (S-1 plus Temozolomide) in patients with metastatic paraganglioma.

Materials and methods: Retrospectively analyzed the efficacy and safety of STEM chemotherapy (S-1 40-60 mg orally twice daily on days 1-14 plus temozolomide 200-300 mg orally daily on days 10-14 in a 21-day cycle) in patients with metastatic paraganglioma in outpatient clinic of our hospital.

Conference:

Presenting Author: Tan H

Authors: Tan H, Zhao H, Shi S, Jiang L, Chi Y,

Keywords: metastatic paraganglioma, STEM, efficacy,