Burden associated with Multiple Endocrine Neoplasia type 1 (MEN1)

#3114

Introduction: Natural history and especially overall risk of death compared to the general population of multiple endocrine neoplasia type 1 (MEN1) patients is poorly known.

Aim(s): All 1386 MEN1 patient captured in a nationwide cohort were included.

Materials and methods: MEN1 patients' survival was compared with the general French population using simulated controls; for each patient in the cohort, 1000 controls were matched by date of birth, age at inclusion, and sex, using the French life tables and a left-truncated, right-censored survival analysis was performed. The cumulative probability of MEN1-specific surgery and postoperative mortality was assessed. Surgical sequences through a sunburst chart was then analysed.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Gaujoux S

Authors: Gaujoux S, Martin G, Mirallié E, Pattou F, Carnaille B,

Keywords: multiple endocrine neoplasia, men1, survival, surgery, natural history,